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Towards a Zinc‐Catalyzed Asymmetric Hydrogenation/Transfer Hydrogenation of Imines
Author(s) -
Werkmeister Svenja,
Fleischer Steffen,
Junge Kathrin,
Beller Matthias
Publication year - 2012
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201200309
Subject(s) - transfer hydrogenation , denticity , trifluoromethanesulfonate , chemistry , zinc , catalysis , asymmetric hydrogenation , noyori asymmetric hydrogenation , ligand (biochemistry) , organic chemistry , enantioselective synthesis , combinatorial chemistry , ruthenium , crystal structure , receptor , biochemistry
The first asymmetric hydrogenation/transfer hydrogenation of imines to amines using zinc(II) triflate in combination with chiral ligands is described. The monodentate binaphthophosphepine ligand ( 3g ) provided the highest enantioselectivities. Using different imines, the corresponding amines were obtained in moderate yields and enantioselectivities.