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Cover Picture: Seed‐mediated Growth of Gold inside Hollow Silica Nanospheres for Sensing Peroxide and Glucose Concentrations (Chem. Asian J. 1/2012)
Author(s) -
Ha TaeLin,
Shin Jongmin,
Lim Choon Woo,
Lee In Su
Publication year - 2012
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201190055
Subject(s) - nanoreactor , nanoshell , biomolecule , biosensor , colloidal gold , selectivity , chemistry , nanoparticle , nanotechnology , catalysis , materials science , combinatorial chemistry , chemical engineering , organic chemistry , engineering
A common limitation of gold nanoparticle (Au NP)‐based sensing in natural samples is that non‐specific binding of biomolecules on the Au NP surface interferes in sensing systems and causes a reduction in the selectivity and sensitivity. To circumvent such a limitation, a recently developed hollow nanoreactor with a nanorattle structure, consisting of a porous silica nanoshell and an entrapped Au NP, was employed. As described in their Communication on page 36 ff., I. S. Lee et al. report that the catalytic Au growth inside the protected cavity, which is accompanied by an SPR enhancement, allows for the quantitative detection of H 2 O 2 and glucose concentrations, even in the presence of the interfering BSA proteins.