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Chemical Synthesis of the Englerins
Author(s) -
Pouwer Rebecca H.,
Richard JeanAlexandre,
Tseng ChihChung,
Chen David Y.K.
Publication year - 2012
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201100780
Subject(s) - battle , natural product , natural (archaeology) , engineering ethics , nanotechnology , psychology , chemistry , engineering , biology , history , materials science , stereochemistry , paleontology , archaeology
In the long lasting battle against cancer, Nature sometimes gives a helping hand to researchers to find new drugs for the treatment of diseases and improvement of patients′ well‐being. Englerin A has emerged as a promising anticancer candidate as well as being an exciting synthetic challenge for organic chemists. This focus review summarizes the total syntheses reported to date and the synthetic approaches toward analogues of this fascinating natural product.