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Rasta Resin–PPh 3 –NBn i Pr 2 and its Use in One‐Pot Wittig Reaction Cascades
Author(s) -
Teng Yan,
Lu Jinni,
Toy Patrick H.
Publication year - 2012
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201100721
Subject(s) - wittig reaction , bifunctional , reagent , phosphine oxide , aldol reaction , chemistry , phosphine , organic chemistry , amine gas treating , catalysis , combinatorial chemistry
A new triarylphosphine–tertiary amine bifunctional polymeric reagent has been prepared and used effectively in a variety of one‐pot Wittig reactions . The design of this reagent resolved a deficiency of a previously reported related material, and allowed it to perform more efficiently in such reactions. Furthermore, it was readily recyclable, and was also successfully applied in cascade processes involving one‐pot Wittig reactions followed by either a conjugate reduction or a reductive aldol reaction . In these reaction cascades, the phosphine oxide groups generated in the Wittig reaction served as the catalyst for the subsequent reaction.