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Heuristic Chemistry—Elimination Reactions
Author(s) -
Graulich Nicole,
Hopf Henning,
Schreiner Peter R.
Publication year - 2011
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201100110
Subject(s) - elimination reaction , chemistry , heuristic , mnemonic , organic reaction , reductive elimination , computational chemistry , combinatorial chemistry , computer science , organic chemistry , psychology , artificial intelligence , catalysis , cognitive psychology
Besides additions and substitutions, elimination reactions play a fundamental role in organic synthesis. However, conceptual reviews of known 1, x ‐elimination patterns that go beyond the typical olefin‐forming 1,2‐eliminations are scarce. To develop a broader understanding of elimination reactions, we follow a heuristic approach and deduce recurrent reaction patterns from traditional and specific elimination reactions. Our work demonstrates that 1, x ‐elimination reactions and their outcomes can be easily rationalized by defined mnemonic categories.
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