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A Photostable Near‐Infrared Protein Labeling Dye for In Vivo Imaging
Author(s) -
Samanta Animesh,
Vendrell Marc,
Yun SeongWook,
Guan Zhenping,
Xu QingHua,
Chang YoungTae
Publication year - 2011
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201100041
Subject(s) - in vivo , fluorescence , fluorescent protein , near infrared spectroscopy , chemistry , computer science , infrared , computational biology , nanotechnology , biochemistry , materials science , neuroscience , biology , green fluorescent protein , optics , microbiology and biotechnology , gene , physics
A NIR death experience : A highly photostable NIR protein‐labeling dye ( CyNE790 ) that maintained excellent fluorescent properties after protein conjugation has been synthesized. Furthermore, the adequacy of the dye for NIR imaging was confirmed by showing that the recognition properties of a labeled anti‐EGFR antibody remained unaffected.