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Chiral Separation by a Pseudo Membrane in a Triple‐Laminar Flow with a Microfluidic Contactor
Author(s) -
Yoon TaeHo,
Hong LanYoung,
Kim DongPyo
Publication year - 2011
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201000798
Subject(s) - contactor , chromatography , membrane , chemistry , ionic liquid , aqueous solution , microfluidics , laminar flow , hydrolysis , chemical engineering , organic chemistry , materials science , nanotechnology , catalysis , biochemistry , power (physics) , physics , quantum mechanics , engineering , thermodynamics
A split personality : The first simultaneous reaction/separation of chiral compounds in a continuous process in an inorganic polymer‐chip device affords the rapid and continuous separation of chiral compounds. Selective esterification of ( S )‐ibuprofen by lipase in organic mediums was followed by transportation of the ( S )‐ibuprofen ester through an ionic liquid as a pseudo‐membrane and finalized by hydrolytic recovery in the aqueous layer.