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Highly Effective Pd‐Catalyzed ortho Olefination of Acetanilides: Broad Substrate Scope and High Tolerability
Author(s) -
Kim Byung Seok,
Jang Chungsik,
Lee Dong Jin,
Youn So Won
Publication year - 2010
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201000613
Subject(s) - acetanilide , tolerability , scope (computer science) , substrate (aquarium) , catalysis , chemistry , combinatorial chemistry , organic chemistry , computer science , medicine , biology , pharmacology , adverse effect , ecology , programming language
Bring it on! An effective Pd‐catalyzed ortho olefination of various acetanilides has been developed. This transformation has a broad substrate scope and wide functional‐group tolerability, regardless of the electronic and steric properties of acetanilide substrates, providing a straightforward access to highly functionalized arenes.