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Seven New Monoterpenoid Indole Alkaloids from Gelsemium elegans
Author(s) -
Yamada Yousuke,
Kitajima Mariko,
Kogure Noriyuki,
Wongseripipatana Sumphan,
Takayama Hiromitsu
Publication year - 2011
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201000538
Subject(s) - indole alkaloid , stereochemistry , alkaloid , moiety , chemistry , indole test , aminal , residue (chemistry) , ketone , organic chemistry
Seven new indole alkaloids were isolated from the roots of Gelsemium elegans Benth. and their structures were determined by spectroscopic analysis and chemical transformation from known alkaloids. Kounaminal ( 1 ) is a new koumine‐type alkaloid that contains an unusual aminal moiety. Humantenoxenine ( 2 ) and 15‐hydroxyhumantenoxenine ( 3 ) are humantenine‐type alkaloids that contain a novel β‐amino‐α,β‐unsaturated ketone residue. The other four novel alkaloids are two gelsedilam‐related and two gelsenicine‐related alkaloids.