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Facile and Efficient Reduction of Ketones in the Presence of Zinc Catalysts Modified by Phenol Ligands
Author(s) -
Enthaler Stephan,
Eckhardt Björn,
Inoue Shigeyoshi,
Irran Elisabeth,
Driess Matthias
Publication year - 2010
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201000317
Subject(s) - hydrosilylation , zinc , phenol , catalysis , aryl , chemistry , alkyl , functional group , reduction (mathematics) , organic chemistry , combinatorial chemistry , in situ , ketone , polymer , geometry , mathematics
In the present study, the zinc‐catalyzed hydrosilylation of various ketones to give their corresponding alcohols has been examined in detail. Diethyl zinc that can be modified by easily accessible phenol ligands allows the efficient reduction of various aryl and alkyl ketones. By using a practical in situ catalyst, excellent turnover frequencies up to 1000 h −1 and a broad functional group tolerance were achieved.