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Palladium‐Catalyzed Intramolecular Carboacetoxylation of 4‐Pentenyl‐Substituted Malonate Esters with Iodobenzene Diacetate
Author(s) -
Fujino Daishi,
Yorimitsu Hideki,
Oshima Koichiro
Publication year - 2010
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201000194
Subject(s) - iodobenzene , palladium , malonate , intramolecular force , catalysis , chemistry , cyclopentanes , organic chemistry , bicyclic molecule , medicinal chemistry
The motorcyclization diaries : Palladium‐catalyzed intramolecular carboacetoxylation of 4‐pentenyl‐substituted malonates proceeds with the aid of titanium tetraisopropoxide and iodobenzene diacetate. The transformation represents the first Pd II /Pd IV catalytic oxidative process that forms an C sp 3 C sp 3 bond as well as a useful method for the synthesis of acetoxymethyl‐substituted cyclopentanes or bicyclic lactones.