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Allylic Imidate Rearrangements Catalyzed by Planar Chiral Palladacycles
Author(s) -
Nomura Hiroshi,
Richards Christopher J.
Publication year - 2010
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201000131
Subject(s) - allylic rearrangement , catalysis , chemistry , planar , combinatorial chemistry , computer science , organic chemistry , computer graphics (images)
The discovery that palladacycles are efficient catalysts for the allylic imidate rearrangement has resulted in the successful application of several such complexes to this reaction based on planar chiral iron and cobalt containing metallocenes. These palladacycles enable the efficient and highly enantioselective synthesis of a wide variety of protected allylic amines, which are valuable building blocks for use in asymmetric synthesis .