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An Effective Preparation of Sulfonyl‐ or Sulfinyl‐Substituted Fluorinated Alkenes and their Stereoselective Addition–Elimination Reactions with Organocuprates
Author(s) -
Yamada Shigeyuki,
Shimoji Kanoko,
Takahashi Toshio,
Konno Tsutomu,
Ishihara Takashi
Publication year - 2010
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201000022
Subject(s) - stereoselectivity , chemistry , sulfone , sulfonyl , sulfoxide , organic chemistry , addition reaction , sequence (biology) , elimination reaction , catalysis , biochemistry , alkyl
Treatment of trifluorovinyl‐ or pentafluoropropen‐1‐yl sulfone or sulfoxide, which are easily prepared from commercially available 1,2‐dibromofluoroalkanes, with various organocuprates affords substitution or β‐reduction products in good to excellent yields through an addition–elimination reaction sequence.