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Recent Developments in Asymmetric Transfer Hydrogenation with Hantzsch Esters: A Biomimetic Approach
Author(s) -
You ShuLi
Publication year - 2007
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.200700081
Subject(s) - transfer hydrogenation , chemistry , combinatorial chemistry , organic chemistry , catalysis , ruthenium
By utilizing Hantzsch esters as the hydrogen source, asymmetric transfer hydrogenation of CC, CN, and CO is realized in the presence of an organocatalyst or a metal–ligand complex, thus affording versatile chiral building blocks in high yields with excellent enantioselectivities under mild conditions. A detailed discussion of recent findings and an assessment of this biomimetic approach are presented in this review.