On the Alert for Cytokine Storm: Immunopathology in  COVID ‐19 | Zendy

Henderson Lauren A. | Zendy; Canna Scott W. | Zendy; Schulert Grant S. | Zendy; Volpi Stefano | Zendy; Lee Pui Y. | Zendy; Kernan Kate F. | Zendy; Caricchio Roberto | Zendy; Mahmud Shawn | Zendy; Hazen Melissa M. | Zendy; Halyabar Olha | Zendy; Hoyt Kacie J. | Zendy; Han Joseph | Zendy; Grom Alexei A. | Zendy; Gattorno Marco | Zendy; Ravelli Angelo | Zendy; Benedetti Fabrizio | Zendy; Behrens Edward M. | Zendy; Cron Randy Q. | Zendy; Nigrovic Peter A. | Zendy

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On the Alert for Cytokine Storm: Immunopathology in COVID ‐19

Author(s) -

Henderson Lauren A.,

Canna Scott W.,

Schulert Grant S.,

Volpi Stefano,

Lee Pui Y.,

Kernan Kate F.,

Caricchio Roberto,

Mahmud Shawn,

Hazen Melissa M.,

Halyabar Olha,

Hoyt Kacie J.,

Han Joseph,

Grom Alexei A.,

Gattorno Marco,

Ravelli Angelo,

Benedetti Fabrizio,

Behrens Edward M.,

Cron Randy Q.,

Nigrovic Peter A.

Publication year - 2020

Publication title -

arthritis and rheumatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.106

H-Index - 314

eISSN - 2326-5205

pISSN - 2326-5191

DOI - 10.1002/art.41285

Subject(s) - cytokine storm , cytokine , immunopathology , covid-19 , medicine , cytokine release syndrome , multidisciplinary approach , storm , immunology , intensive care medicine , disease , virology , infectious disease (medical specialty) , meteorology , geography , outbreak , social science , sociology

Poor outcomes in COVID‐19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve limited health care resources. While studies are ongoing, extrapolating from clinical experience in cytokine storm syndromes may benefit the multidisciplinary teams caring for patients with severe COVID‐19.

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