Premium
Germinal Centers in Diagnostic Biopsies of Patients With Primary Sjögren's Syndrome Are Not a Risk Factor for Non‐Hodgkin's Lymphoma but a Reflection of High Disease Activity: Comment on the Article by Sène et al
Author(s) -
Haacke Erlin A.,
Vegt Bert,
Vissink Arjan,
Spijkervet Fred K. L.,
Bootsma Hendrika,
Kroese Frans G. M.
Publication year - 2019
Publication title -
arthritis and rheumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.106
H-Index - 314
eISSN - 2326-5205
pISSN - 2326-5191
DOI - 10.1002/art.40715
Subject(s) - medicine , disease , germinal center , risk factor , lymphoma , hodgkin lymphoma , dermatology , pathology , immunology , antibody , b cell
With great interest we have read the article of Sène et al. (1) in which ectopic germinal centres (GCs) in labial gland biopsies of primary Sjögren syndrome (pSS) patients were found predictive for Non-Hodgkin's lymphoma (NHL) development later in the disease. In the univariate analysis the presence of GCs in these biopsies was not significantly different between pSS patients that developed NHL or pSS patients that did not. This article is protected by copyright. All rights reserved.