Open AccessTh1/Th2 cytokine balance in arthritis
Author(s) -
Miossec Pierre,
Berg Wim Van Den
Publication year - 1997
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780401203
Subject(s) - citation , medicine , library science , computer science
The contribution of T cells to the pathogenesis of rheumatoid arthritis (RA) has been a matter of debate which is addressed in a number of reviews and chapters of this book 1-3. The contribution of monocytes through the production of proinflammatory cytokines has been simpler to demonstrate 4. Accordingly, Interleukin (IL)-1 and tumor necrosis factor (TNF)a have been selected as important therapeutic targets 5.