Open AccessTreatment of stiff‐man syndrome with intravenous immune globulin
Author(s) -
Karlson Elizabeth W.,
Sudarsky Lewis,
Ruderman Eric,
Pierson Susan,
Scott Mary,
Helfgott Simon M.
Publication year - 1994
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780370621
Subject(s) - medicine , diazepam , refractory (planetary science) , disease , immune system , gamma globulin , antibody , anesthesia , immunology , physics , astrobiology
Objective. To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff‐man syndrome (SMS).Methods. An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids.Results. All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function.Conclusion. IVIG may be useful for the treatment of SMS.