Treatment of stiff‐man syndrome with intravenous immune globulin | Zendy

Karlson Elizabeth W. | Zendy; Sudarsky Lewis | Zendy; Ruderman Eric | Zendy; Pierson Susan | Zendy; Scott Mary | Zendy; Helfgott Simon M. | Zendy

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Treatment of stiff‐man syndrome with intravenous immune globulin

Author(s) -

Karlson Elizabeth W.,

Sudarsky Lewis,

Ruderman Eric,

Pierson Susan,

Scott Mary,

Helfgott Simon M.

Publication year - 1994

Publication title -

arthritis & rheumatism

Language(s) - English

Resource type - Journals

eISSN - 1529-0131

pISSN - 0004-3591

DOI - 10.1002/art.1780370621

Subject(s) - medicine , diazepam , refractory (planetary science) , disease , immune system , gamma globulin , antibody , anesthesia , immunology , physics , astrobiology

Objective. To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff‐man syndrome (SMS).Methods. An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids.Results. All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function.Conclusion. IVIG may be useful for the treatment of SMS.

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