Open AccessEffect of the thiol group on experimental gold‐induced autoimmunity
Author(s) -
Tournade Hervé,
Guery JeanCharles,
Pasquier Régine,
Vial MarieCécile,
Mandet Chantal,
Druet Elvira,
Dansette Patrick M.,
Druet Philippe,
Pelletier Lucette
Publication year - 1991
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780341219
Subject(s) - autoimmunity , thiol , sulfur , chemistry , immunology , medicine , immune system , biochemistry , organic chemistry
Brown Norway rats injected with aurothiopro‐panolsulfonate sodium salt develop systemic autoimmunity. The aim of this study was to assess the influence of the sulfur‐containing group in this experimental model of gold‐induced autoimmunity. It was shown that the sulfur‐containing group does not induce autoimmunity of itself, but potentiates the immunotoxic effects of gold.