Open AccessSystemic sclerosis associated with cutaneous exposure to solvent: Case report and review of the literature
Author(s) -
Brasington Richard D.,
ThorpeSwenson Amy Jo
Publication year - 1991
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780340516
Subject(s) - organic solvent , multiple sclerosis , scleroderma (fungus) , etiology , dermatology , medicine , naphthalene , systemic lupus , occupational exposure , xylene , pathology , chemistry , immunology , organic chemistry , benzene , disease , environmental health , chemical engineering , inoculation , engineering
Sclerodermatous skin changes and systemic sclerosis have been reported to occur as a result of contact with several different organic solvents. We describe a 41‐year‐old man who developed systemic sclerosis after working for 15 years in a foundry, where he had extensive cutaneous contact with multiple organic solvents (trichloroethane, xylene, trimethylbenzene, and naphthalene). Cutaneous exposure to organic solvents may be a factor in the etiology of some cases of systemic sclerosis.