Systemic sclerosis associated with cutaneous exposure to solvent: Case report and review of the literature | Zendy

Brasington Richard D. | Zendy; ThorpeSwenson Amy Jo | Zendy

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Systemic sclerosis associated with cutaneous exposure to solvent: Case report and review of the literature

Author(s) -

Brasington Richard D.,

ThorpeSwenson Amy Jo

Publication year - 1991

Publication title -

arthritis & rheumatism

Language(s) - English

Resource type - Journals

eISSN - 1529-0131

pISSN - 0004-3591

DOI - 10.1002/art.1780340516

Subject(s) - organic solvent , multiple sclerosis , scleroderma (fungus) , etiology , dermatology , medicine , naphthalene , systemic lupus , occupational exposure , xylene , pathology , chemistry , immunology , organic chemistry , benzene , disease , environmental health , chemical engineering , inoculation , engineering

Sclerodermatous skin changes and systemic sclerosis have been reported to occur as a result of contact with several different organic solvents. We describe a 41‐year‐old man who developed systemic sclerosis after working for 15 years in a foundry, where he had extensive cutaneous contact with multiple organic solvents (trichloroethane, xylene, trimethylbenzene, and naphthalene). Cutaneous exposure to organic solvents may be a factor in the etiology of some cases of systemic sclerosis.

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