Development of selective igm deficiency in systemic lupus erythematosus patients with disease of long duration | Zendy

Saiki Osamu | Zendy; Saeki Yukihiko | Zendy; Tanaka Toshio | Zendy; Doi Satoru | Zendy; Hara Hideki | Zendy; Negoro Shigeru | Zendy; Igarashi Tsuyoshi | Zendy; Kishimoto Susumu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Development of selective igm deficiency in systemic lupus erythematosus patients with disease of long duration

Author(s) -

Saiki Osamu,

Saeki Yukihiko,

Tanaka Toshio,

Doi Satoru,

Hara Hideki,

Negoro Shigeru,

Igarashi Tsuyoshi,

Kishimoto Susumu

Publication year - 1987

Publication title -

arthritis & rheumatism

Language(s) - English

Resource type - Journals

eISSN - 1529-0131

pISSN - 0004-3591

DOI - 10.1002/art.1780301112

Subject(s) - medicine , antibody , immunology , lupus erythematosus , disease , connective tissue disease , immunoglobulin m , immunopathology , gastroenterology , autoimmune disease , immunoglobulin g

Statistical analysis of serum immunoglobulin levels in 54 systemic lupus erythematosus (SLE) patients showed a decrease in serum IgM (normal 77 ± 26 mg/dl; P < 0.001) that was closely related to disease duration. The longer the duration of SLE, the more striking the decrease in serum levels of IgM (r = −0.74, P<0.01). Selective IgM deficiency (<47 mg/dl) occurred in SLE patients whose disease was clinically inactive or less active.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research