Paget's disease and osteoarthritis

Paget’s disease of bone is a chronic disorder of accelerated bone break down (resorption) and subsequent bone formation. This occurs in an uncoordinated and unregulated fashion resulting in expanded, misshapen bones. These bones are thickened, but fragile. Active Paget’s can cause pain in the affected bones, but the pain can also be due to other complications of the condition. These include tiny cracks (micro fractures), complete breaks (fractures), mechanical problems related to the deformity putting stress on joints and soft tissues and also nerve entrapment by expanded bone. Another possible cause of pain is the development of wear and tear in the neighbouring joints. This is called osteoarthritis (OA).