Scleromyxedema with systemic involvement mimics rheumatic diseases | Zendy

Fudman Edward J. | Zendy; Golbus Joseph | Zendy; Ike Robert W. | Zendy

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Scleromyxedema with systemic involvement mimics rheumatic diseases

Author(s) -

Fudman Edward J.,

Golbus Joseph,

Ike Robert W.

Publication year - 1986

Publication title -

arthritis & rheumatism

Language(s) - English

Resource type - Journals

eISSN - 1529-0131

pISSN - 0004-3591

DOI - 10.1002/art.1780290716

Subject(s) - medicine , sclerodactyly , dermatology , systemic disease , myxedema , connective tissue disease , scleroderma (fungus) , dysphagia , pathology , dermis , dermatomyositis , monoclonal gammopathy , disease , immunology , autoimmune disease , monoclonal , surgery , calcinosis , monoclonal antibody , thyroid , inoculation , calcification , antibody

Scleromyxedema is an infiltrative skin disease produced by hyaluronic acid deposition in the dermis. A benign monoclonal gammopathy is usually present. We report 2 patients with scleromyxedema and systemic illnesses. Both patients had muscle weakness, dysphagia, and weight loss in addition to the skin changes. One also had sclerodactyly, telangiectasias, and Raynaud's phenomenon. Scleromyxedema with systemic involvement may mimic rheumatic diseases.

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