Open AccessAngiographic findings in mixed connective tissue disease. Correlation with fingernail capillary photomicroscopy and digital photoplethysmography findings
Author(s) -
Peller Jeffrey S.,
Gabor Gary T.,
Porter John M.,
Bennett Robert M.
Publication year - 1985
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780280707
Subject(s) - photoplethysmogram , medicine , connective tissue , mixed connective tissue disease , connective tissue disease , microcirculation , pathology , radiology , disease , autoimmune disease , filter (signal processing) , computer science , computer vision
Thirteen patients with mixed connective tissue disease underwent hand angiography to assess the degree of vascular abnormalities and their correlation to nailfold capillary microscopy and digital photoplethysmography findings. Organic obstruction was found in 60% of ulnar arteries, 87% of superficial arches, 13% of deep arches, and 65% of digital arteries. Fingernail capillary abnormalities were seen in 90% of patients. Normal photoplethysmography results had a predictive value of 91% for identifying digits without bilateral occlusions. These findings indicate a hitherto unrecognized propensity for disease of both small and medium‐sized vessels in patients with mixed connective tissue disease.