Open AccessChanges in vascular endothelium related to lymphocyte collections in diseased synovia
Author(s) -
Freemont Anthony J.,
Jones Carolyn J. P.,
Bromley Michael,
Andrews Paul
Publication year - 1983
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780261203
Subject(s) - pathogenesis , endothelium , pathology , high endothelial venules , medicine , population , immunology , lymphocyte , lymph node , lymph , environmental health
A population of small blood vessels are described in the synovia of patients with a number of different arthropathies. These vessels are identical to the high endothelial venules (HEV) of lymph node paracortex, known to be the site of lymphocyte diapedesis from blood to tissues. The significance of this finding and its possible role in the pathogenesis of inflammatory arthritides are discussed.