Open AccessBone cell cultures as an experimental model
Author(s) -
Wong Glenda L.
Publication year - 1980
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780231003
Subject(s) - phenotype , bone cell , cell , cell type , hormone , microbiology and biotechnology , biology , pathology , medicine , endocrinology , biochemistry , gene
The isolation and separation of bone cells with populations enriched for osteoclastic or osteoblastic phenotypes are described. Such systems offer the opportunity to compare and contrast the controls exerted by hormones, ions, and other agents on the functions of the individual bone cell types and may in the future provide explanations for the changes seen in bone tissue in various diseased states.