Open AccessRegional migratory osteoporosis. a denervation disease
Author(s) -
Clay Mccord W.,
Nies Kenneth M.,
Campion David S.,
Louie James S.
Publication year - 1978
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780210715
Subject(s) - denervation , medicine , etiology , osteoporosis , atrophy , pathogenesis , disease , pathology
Regional migratory osteoporosis is an uncommon entity characterized by sudden attacks of migrating lower extremity paraarticular pain, local edema, and muscle atrophy; the disease is verified by radiologic demineralization and bone scan uptake. The etiology and pathogenesis are unknown. We describe a case of regional migratory osteoporosis followed over nine years by serial electromyographic studies documenting denervation patterns coincident in time and location of each acute attack. The substantiation of denervation in regional migratory osteoporosis is of both diagnostic and pathogenetic significance.