Open AccessHodgkin's disease presenting as relapsing polychondritis a previously undescribed association
Author(s) -
Miller Stephen B.,
Donlan Charles J.,
Roth Steven B.
Publication year - 1974
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780170515
Subject(s) - relapsing polychondritis , medicine , prednisone , malignancy , disease , autoimmune disease , chondropathy , dermatology , systemic disease , pathology , osteoarthritis , articular cartilage , alternative medicine
Relapsing polychondritis is a rare syndrome thought to be autoimmune in nature and characterized by inflammation and degeneration of cartilage. The association with a reticuloendothelial malignancy has not previously been reported. A 46‐year‐old man presented typical clinical manifestations of relapsing polychondritis requiring 30 mg of prednisone daily for suppression. However within 6 months he developed chronic fatigue, fevers, night sweats, adenopathy, and splenomegaly leading to the diagnosis of Hodgkin's disease.