Open AccessFavorable outcome in diffuse proliferative glomerulonephritis of systemic lupus erythematosus
Author(s) -
Epstein Wallace V.,
Grausz Henry
Publication year - 1974
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780170205
Subject(s) - prednisone , medicine , chlorambucil , systemic disease , glomerulonephritis , biopsy , lupus erythematosus , cyclophosphamide , immunology , immunopathology , chemotherapy , kidney , antibody
Life table analysis of 31 patients with biopsy proven diffuse proliferative glomerulonephritis due to Systemic Lupus Erythematosus reveals a 77.7% five‐year survival. Patients with similar lesions have, in the past, had an approximate 20% five‐year survival. The improved survival is attributed to the combined use of prednisone and chlorambucil and a panel of frequently repeated laboratory tests that provides a guide to the activity of the systemic disease.