Open AccessAdenocarcinoma of the lung during azathioprine therapy
Author(s) -
McAdam Lawrence,
Paulus Harold E.,
Peter James B.
Publication year - 1974
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780170114
Subject(s) - azathioprine , medicine , prednisone , malignancy , adenocarcinoma , lung , lupus nephritis , adenocarcinoma of the lung , immunosuppression , lung transplantation , immunology , gastroenterology , cancer , disease
Reports of malignancies developing during immunosuppressive therapy have been difficult to interpret because of concurrent prednisone administration in all cases, and organ transplantation in most. This communication reports an adenocarcinoma of the lung in a 39‐year‐old woman with lupus nephritis who had been treated only with azathioprine during the previous 4 years. This suggests that corticosteroids and transplanted antigens may not be prerequisites for the development of a malignancy during immunosuppressive therapy.