Open AccessSynovial Iron Deposition in Rheumatoid Arthritis
Author(s) -
Bennett Robert M.,
Williams E. D.,
Lewis S. M.,
Holt P. J. L.
Publication year - 1973
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780160303
Subject(s) - rheumatoid arthritis , hemoglobin , deposition (geology) , medicine , gastroenterology , arthritis , iron levels , chemistry , endocrinology , surgery , pathology , biology , paleontology , sediment
An isotope ferrokinetic study has been used to study the rate of iron deposition in 13 rheumatoid knees. Iron accumulation occurred only after incorporation of labelled iron into circulating erythrocytes, suggesting that intermittent intraarticular hemorrhages were the source of the deposits. The mean iron accumulation was 1.25 mg/knee/day representing a mean intraarticular blood loss of 3.58 ml. There was no correlation between the degree of iron deposition and the hemoglobin, platelet count or serum iron.