Open AccessUltrastructural comparison of rheumatoid and nonrheumatoid synovial fibroblasts grown in tissue culture
Author(s) -
WynneRoberts C. Rosales,
Castor C. William
Publication year - 1972
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780150110
Subject(s) - ultrastructure , acid phosphatase , pathology , rheumatoid arthritis , tissue culture , biology , electron microscope , fibroblast , cell , synovial membrane , cell culture , chemistry , microbiology and biotechnology , immunology , medicine , biochemistry , enzyme , in vitro , genetics , physics , optics
Ten rheumatoid and seven nonrheumatoid tissue culture strains of synovial fibroblasts were studied biochemically and by electron microscopy. No obvious differences in the ultrastructure of the rheumatoid and nonrheumatoid cell strains were detected. Acid phosphatase and β‐glucuronidase measurements were similar in the two groups. No morphologic evidence of an infectious agent was found in any of the cell strains. The diverse morphology found in both groups of cells is described.