D‐Penicillamine in rheumatoid arthritis | Zendy

Zuckner Jack | Zendy; Ramsey Robert H. | Zendy; Dorner Robert W. | Zendy; Gantner Jr George E. | Zendy

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D‐Penicillamine in rheumatoid arthritis

Author(s) -

Zuckner Jack,

Ramsey Robert H.,

Dorner Robert W.,

Gantner Jr George E.

Publication year - 1970

Publication title -

arthritis & rheumatism

Language(s) - English

Resource type - Journals

eISSN - 1529-0131

pISSN - 0004-3591

DOI - 10.1002/art.1780130205

Subject(s) - penicillamine , rheumatoid arthritis , medicine , ceruloplasmin , erythrocyte sedimentation rate , rheumatoid factor , titer , gastroenterology , arthritis , lymphocyte , antibody , immunology

D‐penicillamine was administered to 15 patients with rheumatoid arthritis. A fall in the titer of rheumatoid factor was demonstrated in all patients. The sedimentation rate decreased in most patients. There was no consistent alteration in immunoglobulins A, G or M or in lymphocyte transformation attributable to penicillamine. Ceruloplasmin serum levels were lowered significantly in 7 patients. Clinical improvement in the arthritis resulted in 10 patients.

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