Open AccessRadioimmunoassay of rheumatoid factor
Author(s) -
Franchimont P.,
Suteanu S.
Publication year - 1969
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780120504
Subject(s) - rheumatoid factor , radioimmunoassay , rheumatoid arthritis , globulin , immunology , medicine , chemistry , endocrinology
A radioimmunological method for assaying rheumatoid factor is proposed and analyzed. The method is based on the reaction between rheumatoid factor, either purified or present in serum, and purified labeled yg globulin. This assay permits a quantitative estimation of rheumatoid factor levels in rheumatoid‐positive serum and provides evidence that rheumatoid‐negative serum contains factors which can bind labeled yg globulin. Normal serum assayed by this method does not ordinarily contain such factors.