Open AccessAortic insufficiency in systemic lupus erythematosus
Author(s) -
Shulman Herbert J.,
Christian Charles L.
Publication year - 1969
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780120210
Subject(s) - medicine , endocarditis , systemic disease , aortic valve , marfan syndrome , cardiology , aortitis , connective tissue disease , aortic valve insufficiency , surgery , aorta , immunopathology , autoimmune disease , disease
Three cases of systemic lupus erythematosus (SLE) with aortic insufficiency are presented. One patient had Libman‐Sacks endocarditis at necropsy. Another had aortitis and pancarditis. The third had a fenestrated aortic valve showing mucoid degeneration, similar to the lesions described in Marfan's syndrome and the “floppy valve” syndrome, and had a successful insertion of a prosthetic valve. Two patients with subcutaneous “rheumatoid nodules” had persistently negative latex fixation tests.