Synovial collagenase: Its presence in culture from joint disease of diverse etiology | Zendy

Harris Edward D. | Zendy; Cohen George L. | Zendy; Krane Stephen M. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Synovial collagenase: Its presence in culture from joint disease of diverse etiology

Author(s) -

Harris Edward D.,

Cohen George L.,

Krane Stephen M.

Publication year - 1969

Publication title -

arthritis & rheumatism

Language(s) - English

Resource type - Journals

eISSN - 1529-0131

pISSN - 0004-3591

DOI - 10.1002/art.1780120206

Subject(s) - collagenase , synovitis , rheumatoid arthritis , medicine , synovectomy , synovial membrane , arthritis , pathology , biopsy , microbial collagenase , joint disease , osteoarthritis , chemistry , enzyme , biochemistry , alternative medicine

Closed needle biopsy of synovium from inflamed joints yields enough tissue to detect production and/or release of collagenase from these tissues. Collagenase activity was found in synovium from 8 of 8 patients with probable rheumatoid arthritis, in 6 of 9 patients with nonrheumatoid inflammatory synovitis, and in 1 of 6 patients with degenerative joint disease. One of 2 patients with classic rheumatoid arthritis had activity in synovium regrown after synovectomy. Therefore synovial collagenase is not unique to rheumatoid arthritis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research