Open AccessA biochemical and electron microscopy study of rice bodies from rheumatoid patients
Author(s) -
Albrecht Manfred,
Marinetti Guido V.,
Jacox Ralph F.,
Vaughan John H.
Publication year - 1965
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780080605
Subject(s) - electron microscope , synovectomy , mucoproteins , pathology , fibrin , chemistry , neuraminic acid , ultrastructure , degeneration (medical) , rheumatoid arthritis , biology , medicine , biochemistry , sialic acid , immunology , physics , optics
Abstract Rice bodies (corpora oryzoidea) from rheumatoid patients were studied biochemically and by electron microscopy. The data indicate that only a relatively small portion of the rice bodies is identical to fibrin, and the bulk is composed of other fibrinlike mucoproteins and a small amount of lipids. Some lipids and neuraminic acid are located on the surface. The recurrence of rice bodies is prevented by synovectomy. Fibrous rice bodies represent an end product of synovial inflammation, proliferation, and subsequent secondary degeneration.