
Movement and composition of interstitial fluid of cartilage
Author(s) -
Linn Frank C.,
Sokoloff Leon
Publication year - 1965
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780080402
Subject(s) - synovial fluid , ground substance , cartilage , interstitial fluid , resorption , composition (language) , chemistry , viscosity , extracellular fluid , articular cartilage , tissue fluid , anatomy , pathology , biology , medicine , materials science , biochemistry , osteoarthritis , extracellular , composite material , connective tissue , alternative medicine , linguistics , philosophy
A method is described for determining the rate of mechanical expression and resorption of fluid from cartilage and for determining its composition. Human articular cartilage, unlike costal tissue, showed little change in its total or expressible fluid throughout life. The extruded material resembled synovial fluid except for its low protein content and viscosity. It is suggested that the expressed fluid was held osmotically in the ground substance.