Open AccessChloroquine and hydroxychloroyuine therapy in rheumatoid arthritis
Author(s) -
Scull Edward
Publication year - 1962
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780050105
Subject(s) - hydroxychloroquine , chloroquine , rheumatoid arthritis , medicine , placebo , corticosteroid , surgery , immunology , alternative medicine , covid-19 , malaria , pathology , disease , infectious disease (medical specialty)
One hundred and ninety‐six poorly controlled rheumatoid arthritics were divided into three groups: 80 received chloroquine, 80 hydroxychloroquine, and 36 placebo, for an average duration of 24, 18 and 5.2 months respectively. Fifty‐seven per cent of patients were able to reduce or abolish their corticosteroid requirements while on the active drugs under study. It appeared from this study that chloroquine and hydroxychloroquine possessed definite antirheuniatic effect. No serious side effects were observed.