Open AccessThe microscopic structure of normal human synovial tissue
Author(s) -
Castor C. William
Publication year - 1960
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780030205
Subject(s) - vascularity , pathology , hyaluronic acid , anatomy , synovial membrane , biology , chemistry , medicine , rheumatoid arthritis , immunology
Microscopic study of normal synovial tissue from 16 humans of varying age disclosed an architectural pattern which did not vary significantly with age, sex or intra‐articular location. Except for fibrous synovium, the tissue samples were similar in vascularity, number of surface cell layers and in the differential composition of the surface cells. Histochemical procedures delineated a pericellular surface reticulin network but failed to establish the locus of hyaluronic acid synthesis.