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Synthese [ b ]‐kondensierter azepindione durch dealkoxycarbonylierung
Author(s) -
Kunick Conrad
Publication year - 1991
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.2503240910
Subject(s) - azepine , chemistry , toluene , stereochemistry , organic chemistry
Synthesis of [ b ]‐Fused Azepinediones by Dealkoxycarbonylation The 2,3,4,5‐tetrahydro‐1 H ‐1‐benzazepinediones 2 and 5,6,7,8‐tetrahydro‐4 H ‐thieno[3,2‐ b ]azepine‐5,8‐dione (11) are obtained by dealkoxycarbonylation in wet dimethylsulfoxide from fused azepinecarboxylic esters 3 and 10, respectively, 3b and 10 are prepared by Dieckmann reaction with KH in DMF/toluene from diesters 6 and 9, respectively.