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Diastereoselective Synthesis of N ‐Boc‐Norpandamarilactonine‐B and Pandamarilactonine‐A
Author(s) -
Honda Toshio,
Katoh Misugi,
Ushiwata Makoto,
Shigehisa Hiroki
Publication year - 2008
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.200700218
Subject(s) - chemistry , stereochemistry , ring closing metathesis , derivative (finance) , metathesis , salt metathesis reaction , serine , ring (chemistry) , combinatorial chemistry , organic chemistry , enzyme , financial economics , economics , polymerization , polymer
Optically pure N ‐Boc‐norpandamarilactonine‐B was diastereoselectively synthesized starting from L ‐serine by employing a double ring closing metathesis (RCM) of a tetraene derivative as a key reaction. N ‐Boc‐norpandamarilactonine‐B obtained was further converted to pandamarilactonine‐A.
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