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An Improved Synthesis of the Anti‐Picornavirus Flavone 3‐ O ‐Methylquercetin
Author(s) -
Boers Frank,
Deng BoLiang,
Lemière Guy,
Lepoivre Jozef,
De Groot Alex,
Dommisse Roger,
Vlietinck Arnold J.
Publication year - 1997
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19973300909
Subject(s) - chemistry , picornavirus , transformation (genetics) , stereochemistry , biochemistry , rna , gene
Two optimised procedures to synthesise 3‐ O ‐methylquercetin ( 1 ), an important antivirally active flavone, are presented: one is based on an Allan‐Robinson condensation, the other one on a modified phase transfer catalysed Baker‐ Venkataraman transformation.
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