Platelet Aggregation Inhibiting and Anticoagulant Effects of Oligoamines, XXVIII: Oligoamines with Fluorescent Properties. Part C: Fluorescent Oligoamines with Enhanced Hydrophilic Properties | Zendy

Rehse Klaus | Zendy; Seidel Torsten | Zendy

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Platelet Aggregation Inhibiting and Anticoagulant Effects of Oligoamines, XXVIII: Oligoamines with Fluorescent Properties. Part C: Fluorescent Oligoamines with Enhanced Hydrophilic Properties

Author(s) -

Rehse Klaus,

Seidel Torsten

Publication year - 1995

Publication title -

archiv der pharmazie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.468

H-Index - 61

eISSN - 1521-4184

pISSN - 0365-6233

DOI - 10.1002/ardp.19953280208

Subject(s) - fluorescence , platelet aggregation , chemistry , anticoagulant , biophysics , platelet , biology , medicine , physics , quantum mechanics , immunology

Fifteen fluorescent oligoamines with one or two fluorescent groups and two or three basic N‐functions were prepared and tested for antiplatelet activity ( Born ‐test). Five compounds involving three different fluorophores, i.e. 2‐fluorenyl, 1‐pyrenyl, and 9‐phenanthryl, show an IC 50 of 7–11 μmol/L. They are suitable to serve as probes in the field of oligoamine‐biopolymere interactions.

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