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New NO‐Donors with Antithrombotic and Vasodilating Activities, XI: 2‐Nitrosiminobenzimidazoles
Author(s) -
Rehse Klaus,
Birkhofer Gerhard
Publication year - 1995
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19953280114
Subject(s) - antithrombotic , vasodilation , chemistry , pharmacology , medicine
Thirteen 1,3‐disubstituted title compounds were synthesized and tested for their antiplatelet activity ( Born test, collagen). Three derivatives inhibited the platelet aggregation halfmaximally in concentrations < 20 μmol/L.
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