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1,3‐Diphenylpropane‐1,3‐diamines, III: Synthesis of 1,3‐Bis(hydroxy‐halogenophenyl)‐propane‐1,3‐diamines and their Pt(II) Complexes Part A: Synthesis of the Ligands
Author(s) -
Kammermeier Thomas,
Wiegrebe Wolfgang
Publication year - 1994
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19943270903
Subject(s) - chemistry , diastereomer , hydroxylamine , propane , medicinal chemistry , diamine , organic chemistry , combinatorial chemistry
The title diamines were prepared according to von Auwer's/Arakawa's procedures starting from appropriately substituted benzaldehydes and acetophenones via chalcones, addition of two moles of hydroxylamine, reduction, and separation of diastereomers as N,N′‐bisacetamides. ‐ The Pt(II) complexes of the title ligands are described in the following paper.