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Sydnone Derivatives: Synthesis and Antimicrobial Activity Sydnon‐Derivate: Synthese und Wirksamkeit gegen Mikroorganismen
Author(s) -
Pilli Ayyildiz H. Gülhan,
Safak Cihat,
Abbasoǧlu Ufuk
Publication year - 1993
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19933260912
Subject(s) - sydnone , antimicrobial , chemistry , chalcone , biological activity , aryl , alkyl , organic chemistry , stereochemistry , combinatorial chemistry , biochemistry , in vitro , ring (chemistry)
Amongst a number of mesoinoic compounds studied so far, sydnones have attained importance due not only to their structural features and chemical properties, but also to their biological properties. Sydnone derivatives have been extensively studied for their biological activities, the antimicrobial activity of substituted aryl sydnones has been reported. Aryl sydnones are less toxic and more active than alkyl sydnones. Also chalcone analogues are known to have antimicrobial activity.