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Oxazepines and Thiazepines, XXVII: Chemical Transformations of 2,3‐Dihydro‐2‐phenyl‐1,4‐benzoxazepin‐5(4 H )‐one
Author(s) -
Lévai Albert,
Bálint Zoltán
Publication year - 1993
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19933260204
Subject(s) - alkyl , chemistry , reagent , medicinal chemistry , stereochemistry , organic chemistry
N ‐Alkyl ( 2 ‐ 11 ) and N ‐acyl ( 18 ‐ 30 ) derivatives of 2,3‐dihydro‐2‐phenyl‐1,4‐benzoxazepin‐5(4 H )‐one ( 1 ) have been synthesized. 4‐Alkyl‐2,3‐dihydro‐2‐phenyl‐1,4‐benzoxazepin‐5(4 H )‐thiones 12 ‐ 15 arose from compounds 2, 3, 5 , and 6 with Lawesson ' s reagent. Bis‐[2,3‐dihydro‐2‐phenyl‐1,4‐benzoxazepin‐5(4 H )‐onyl]‐alkanes 16 and 17 were prepared from 1 and dihaloalkanes.
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