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Heterocyclic Groups [ b ]‐Annulated to the 1,4‐Benzodiazepine System
Author(s) -
Berghot M. A.
Publication year - 1992
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19923250507
Subject(s) - thiourea , chemistry , ammonium thiocyanate , pyrimidinones , ethyl cyanoacetate , urea , hydroxylamine , thiocyanate , medicinal chemistry , benzodiazepine , ammonium acetate , organic chemistry , biochemistry , malononitrile , receptor , high performance liquid chromatography , catalysis
Abstract Pyrazoles, isoxazoles, pyrimidinones, thiazines, mercaptopyrimidines, pyridones, and triazepinthiones were fused with diazepam (1) by reaction of the arylidenes 2a‐h with hydrazines, hydroxylamine, urea or its derivatives, thiourea, ammonium thiocyanate, ethyl cyanoacetate, and thiosemicarbazide.