Pyridazines, LVII: Synthesis and Cyclocondensation Reactions of (2‐Aminophenyl)‐(4‐pyridazinyl)‐ketone, a New Diaza Isoster of 2‐Aminobenzophenone | Zendy

Haider Norbert | Zendy; Heinisch Gottfried | Zendy; Moshuber Jöran | Zendy

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Pyridazines, LVII: Synthesis and Cyclocondensation Reactions of (2‐Aminophenyl)‐(4‐pyridazinyl)‐ketone, a New Diaza Isoster of 2‐Aminobenzophenone

Author(s) -

Haider Norbert,

Heinisch Gottfried,

Moshuber Jöran

Publication year - 1992

Publication title -

archiv der pharmazie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.468

H-Index - 61

eISSN - 1521-4184

pISSN - 0365-6233

DOI - 10.1002/ardp.19923250212

Subject(s) - chemistry , intramolecular force , ketone , quinazoline , amide , derivative (finance) , condensation reaction , medicinal chemistry , condensation , combinatorial chemistry , stereochemistry , organic chemistry , catalysis , physics , financial economics , economics , thermodynamics

A convenient approach to the new 2‐aminobenzophenone analogue 4 is reported. Condensation reactions of 4 with ortho esters or amide acetals, respectively, followed by intramolecular cyclisations were found to provide smooth access to (4‐pyridazinyl)‐substituted quinolines 10, 13a,b , and the quinazoline derivative 15 .

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